60754

• Gene Symbol: Chuk
• Gene Name: conserved helix-loop-helix ubiquitous kinase
• Gene Aliases: AI256658, Chuk1, Fbx24, Fbxo24, IKBKA, IKK1, Ikka, NFKBIKA
• Chromosome Location: Chr.19: 44073334 - 44107506 on Build GRCm38
• UniGene ID: Mm.3996
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chuk
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162410.1	NP_001155882.1	6	616
	NM_007700.2	NP_031726.2	6	616
GenBank mRNA	AK018671.1	-	6	595
	AK035326.1	-	6	573
	AK150039.1	-	6	595
	AK155328.1	-	6	596
	AK155393.1	-	6	617
	AK164236.1	-	6	617
	BC018243.1	-	6	608	4511275
	U12473.1	-	6	584

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107588, XM_008760418, XM_008760419, XM_006231481, BC168905.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

morphogenesis of an epithelial sheet
protein phosphorylation
I-kappaB phosphorylation
Rho protein signal transduction
lactation
response to organic substance
phosphorylation
signal transduction by protein phosphorylation
osteoclast differentiation
response to lipopolysaccharide
mammary gland epithelial cell proliferation
response to muscle stretch
odontogenesis of dentin-containing tooth
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
striated muscle cell differentiation
mammary gland alveolus development
cellular response to tumor necrosis factor

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding