61163

• Gene Symbol: Dmd
• Gene Name: dystrophin, muscular dystrophy
• Gene Aliases: DXSmh7, DXSmh9, Dp427, Dp71, dys, mdx, pke
• Chromosome Location: Chr.X: 82310713 - 85205050 on Build GRCm38
• UniGene ID: Mm.275608
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dmd
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007868.5	NP_031894.1	3, 4	430
GenBank mRNA	AK044536.1	-	3, 4	230
	AK052856.1	-	3, 4	431
	M68859.1	-	3, 4	403

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004006, NM_004009, NM_004010, NM_004007, NM_000109, and others.
This siRNA also targets the following transcripts in Rat: XM_008773281.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

positive regulation of cell-matrix adhesion
regulation of heart rate
regulation of transcription, DNA-templated
muscle organ development
skeletal muscle tissue development
establishment of blood-nerve barrier
regulation of gene expression
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of neuron projection development
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
regulation of skeletal muscle contraction
myotube cell development
muscle attachment
olfactory nerve structural organization
negative regulation of peptidyl-serine phosphorylation
cellular protein localization
response to muscle stretch
regulation of membrane potential
peptide biosynthetic process
cellular protein complex assembly
neurotransmitter receptor metabolic process
positive regulation of neuron differentiation
muscle cell cellular homeostasis
muscle fiber development
nucleus localization
cardiac muscle contraction
regulation of ryanodine-sensitive calcium-release channel activity
establishment of glial blood-brain barrier
negative regulation of ERK1 and ERK2 cascade
cardiac muscle cell action potential
regulation of cellular response to growth factor stimulus
regulation of voltage-gated calcium channel activity
negative regulation of peptidyl-cysteine S-nitrosylation
positive regulation of sodium ion transmembrane transporter activity

Function(s)

dystroglycan binding
actin binding
structural constituent of cytoskeleton
protein binding
zinc ion binding
structural constituent of muscle
myosin binding
vinculin binding
metal ion binding
nitric-oxide synthase binding