61204

• Gene Symbol: Egfr
• Gene Name: epidermal growth factor receptor
• Gene Aliases: 9030024J15Rik, AI552599, Erbb, Errb1, Errp, Wa5, wa-2, wa2
• Chromosome Location: Chr.11: 16752203 - 16913907 on Build GRCm38
• UniGene ID: Mm.420648
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egfr
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007912.4	NP_031938.1	2	385
	NM_207655.2	NP_997538.1	2	385
GenBank mRNA	AF124513.1	-	2	319
	AF275367.1	-	2	328
	AK004883.1	-	2	386
	AK004911.1	-	2	360
	AK004944.1	-	2	379
	AK134262.1	-	2	359
	BC023729.1	-	2	356	5351807
	L06864.1	-	2	71
	U03425.1	-	2	155
	X59698.1	-	2	264
	X78987.1	-	2	164

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031507, XM_008770418, XM_008770416, XM_008770417, M37394, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
cell morphogenesis
embryonic placenta development
positive regulation of protein phosphorylation
hair follicle development
translation
protein phosphorylation
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
epidermal growth factor receptor signaling pathway
multicellular organism development
salivary gland morphogenesis
learning or memory
cell proliferation
positive regulation of cell proliferation
epidermis development
magnesium ion homeostasis
phosphorylation
single organismal cell-cell adhesion
peptidyl-tyrosine phosphorylation
cerebral cortex cell migration
positive regulation of cell migration
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
positive regulation of superoxide anion generation
positive regulation of catenin import into nucleus
intracellular signal transduction
regulation of cell proliferation
negative regulation of protein catabolic process
positive regulation of phosphorylation
ovulation cycle
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of nitric oxide biosynthetic process
positive regulation of DNA repair
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of vasodilation
negative regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
astrocyte activation
positive regulation of fibroblast proliferation
digestive tract morphogenesis
positive regulation of smooth muscle cell proliferation
neuron projection morphogenesis
positive regulation of epithelial cell proliferation
positive regulation of inflammatory response
regulation of peptidyl-tyrosine phosphorylation
regulation of nitric-oxide synthase activity
response to calcium ion
positive regulation of protein kinase B signaling
positive regulation of synaptic transmission, glutamatergic
morphogenesis of an epithelial fold
response to UV-A
positive regulation of ERK1 and ERK2 cascade
cellular response to amino acid stimulus
cellular response to epidermal growth factor stimulus
cellular response to estradiol stimulus

Function(s)

nucleotide binding
glycoprotein binding
chromatin binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
signal transducer activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
receptor binding
integrin binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
protein kinase binding
protein phosphatase binding
nitric-oxide synthase regulator activity
ubiquitin protein ligase binding
identical protein binding
protein heterodimerization activity
epidermal growth factor binding
actin filament binding