61271

• Gene Symbol: Dyrk1a
• Gene Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
• Gene Aliases: 2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, ENSMUSG00000074897, Gm10783, Mnbh, Mp86, mmb
• Chromosome Location: Chr.16: 94569951 - 94695519 on Build GRCm38
• UniGene ID: Mm.310973
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dyrk1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113389.1	NP_001106860.1	4, 5	481
	NM_007890.2	NP_031916.1	4, 5	740
GenBank mRNA	BC129888.1	-	3, 4	343	40111469
	BC129889.1	-	3, 4	343	40111470
	BC138716.1	-	3, 4	370	8861738
	BC145405.1	-	3, 4	343	9053963
	CB526389.1	-	4, 5	481
	CD540384.1	-	4, 5	456
	U58497.1	-	3, 4	370

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_130438, NM_001396, NM_101395, NM_130436, D85759, and others.
This siRNA also targets the following transcripts in Rat: NM_012791, XM_008768563, XM_006248031, XM_008768565, XM_008768564, and others.

Gene Ontology Categories:

Process(es)

regulation of alternative mRNA splicing, via spliceosome
protein phosphorylation
circadian rhythm
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of DNA damage response, signal transduction by p53 class mediator
protein autophosphorylation
negative regulation of mRNA splicing, via spliceosome
positive regulation of protein deacetylation

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
identical protein binding
protein self-association
tau protein binding