61379

• Gene Symbol: Fgfr3
• Gene Name: fibroblast growth factor receptor 3
• Gene Aliases: CD333, FR3, Fgfr-3, Flg-2, HBGFR, Mfr3, sam3
• Chromosome Location: Chr.5: 33721724 - 33737068 on Build GRCm38
• UniGene ID: Mm.6904
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fgfr3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001163215.2	NP_001156687.1	3	564
	NM_001163216.2	NP_001156688.1	2	333
	NM_001163217.2	NP_001156689.1	2	333
	NM_001205270.1	NP_001192199.1	3	538
	NM_008010.5	NP_032036.2	3	538
GenBank mRNA	AF024638.1	-	2	241
	AK140217.1	-	2	455
	AK143592.1	-	3	471
	AK163495.1	-	1	117
	AK163547.1	-	2	455
	BC053056.1	-	3	448	5708838
	BY732245.1	-	3	502
	CB247234.1	-	3	409
	CD349897.1	-	3	538
	M81342.1	-	3	456
	S56291.1	-	2	283
	X58255.1	-	3	442

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
skeletal system development
positive regulation of endothelial cell proliferation
morphogenesis of an epithelium
lens morphogenesis in camera-type eye
protein phosphorylation
apoptotic process
cell-cell signaling
positive regulation of cell proliferation
negative regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of phospholipase activity
oligodendrocyte development
phosphorylation
peptidyl-tyrosine phosphorylation
substantia nigra development
central nervous system myelination
cell differentiation
bone mineralization
forebrain development
positive regulation of protein ubiquitination
somatic stem cell population maintenance
post-anal tail morphogenesis
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of cell differentiation
negative regulation of mitotic nuclear division
negative regulation of smoothened signaling pathway
protein autophosphorylation
digestive tract morphogenesis
negative regulation of developmental growth
response to axon injury
negative regulation of astrocyte differentiation
inner ear development
negative regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
cartilage development
inner ear receptor cell differentiation
bone morphogenesis
axonogenesis involved in innervation
alveolar secondary septum development
lens fiber cell development
positive regulation of ERK1 and ERK2 cascade
bone maturation
epithelial cell fate commitment
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
cochlea development
positive regulation of canonical Wnt signaling pathway
fibroblast growth factor receptor apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
fibroblast growth factor binding