61402

• Gene Symbol: Eng
• Gene Name: endoglin
• Gene Aliases: AI528660, AI662476, CD105, Endo, S-endoglin
• Chromosome Location: Chr.2: 32646532 - 32682669 on Build GRCm38
• UniGene ID: Mm.225297
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Eng
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001146348.1	NP_001139820.1	4	756
	NM_001146350.1	NP_001139822.1	4	759
	NM_007932.2	NP_031958.2	4	759
GenBank mRNA	AK151302.1	-	4	729
	AK178235.1	-	2	59
	AK187426.1	-	2	59
	AK188120.1	-	2	59
	AY679531.1	-	4	759
	BC029080.1	-	4	673	4168250
	S69407.1	-	5	624
	X77952.1	-	4	759

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
patterning of blood vessels
vasculogenesis
response to hypoxia
positive regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
heart looping
positive regulation of systemic arterial blood pressure
cell migration involved in endocardial cushion formation
regulation of transcription, DNA-templated
protein phosphorylation
cell adhesion
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
heart development
positive regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
cell migration
regulation of transforming growth factor beta receptor signaling pathway
central nervous system vasculogenesis
extracellular matrix disassembly
negative regulation of cell migration
positive regulation of BMP signaling pathway
negative regulation of protein autophosphorylation
positive regulation of collagen biosynthetic process
intracellular signal transduction
wound healing
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
smooth muscle tissue development
artery morphogenesis
venous blood vessel morphogenesis
cell motility
negative regulation of nitric-oxide synthase activity
cell chemotaxis
negative regulation of pathway-restricted SMAD protein phosphorylation
extracellular matrix constituent secretion
detection of hypoxia

Function(s)

transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor, cytoplasmic mediator activity
type II transforming growth factor beta receptor binding
protein binding
galactose binding
glycosaminoglycan binding
type I transforming growth factor beta receptor binding
BMP binding
protein homodimerization activity
transforming growth factor beta binding