61418

• Gene Symbol: Ercc2
• Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 2
• Gene Aliases: AA407812, AU020867, AW240756, CXPD, Ercc-2, XPD
• Chromosome Location: Chr.7: 19382039 - 19395692 on Build GRCm38
• UniGene ID: Mm.36524
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ercc2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007949.4	NP_031975.2	4, 5	270
GenBank mRNA	AK082761.1	-	4, 5	271
	AK141692.1	-	4, 5	289
	U97572.1	-	3, 4	254

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001172809.

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

in utero embryonic development
nucleobase-containing compound metabolic process
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
response to oxidative stress
chromosome segregation
aging
cell proliferation
response to UV
UV protection
post-embryonic development
spinal cord development
hair cycle process
extracellular matrix organization
bone mineralization
central nervous system myelin formation
DNA duplex unwinding
nucleotide-excision repair, DNA incision
multicellular organism growth
hair cell differentiation
embryonic cleavage
erythrocyte maturation
positive regulation of DNA binding
skin development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
hair follicle maturation
hematopoietic stem cell differentiation
regulation of mitotic cell cycle phase transition

Function(s)

nucleotide binding
nucleic acid binding
DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein kinase activity
ATP binding
protein C-terminus binding
ATP-dependent helicase activity
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
5'-3' DNA helicase activity
metal ion binding
protein N-terminus binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding