61635

• Gene Symbol: Gata3
• Gene Name: GATA binding protein 3
• Gene Aliases: Gata-3, jal
• Chromosome Location: Chr.2: 9857078 - 9887950 on Build GRCm38
• UniGene ID: Mm.313866
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gata3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008091.3	NP_032117.1	2	734
GenBank mRNA	AK053728.1	-	1	1141
	AK090089.1	-	2	742
	AK155549.1	-	2	735
	AK156634.1	-	2	721
	AK157625.1	-		354
	AK157939.1	-	2	608
	AK161099.1	-	2	612
	BC062915.1	-	1	330	6826352
	X55123.1	-	1	350

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133293, XM_006254253, XM_008771893, XM_008771894, AB000217, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
in utero embryonic development
cell fate determination
neuron migration
cell activation
positive regulation of cytokine production
kidney development
mesonephros development
lens development in camera-type eye
immune system process
pro-T cell differentiation
aortic valve morphogenesis
cardiac right ventricle morphogenesis
ventricular septum development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
humoral immune response
signal transduction
nervous system development
axon guidance
negative regulation of cell proliferation
male gonad development
post-embryonic development
positive regulation of signal transduction
positive regulation of endothelial cell migration
negative regulation of gene expression
regulation of neuron projection development
phosphatidylinositol 3-kinase signaling
neuron differentiation
T cell differentiation
erythrocyte differentiation
TOR signaling
negative regulation of interferon-gamma production
negative regulation of interleukin-2 production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
T cell differentiation in thymus
negative regulation of mammary gland epithelial cell proliferation
embryonic hemopoiesis
ureter maturation
parathyroid hormone secretion
regulation of cytokine biosynthetic process
norepinephrine biosynthetic process
inner ear morphogenesis
regulation of CD4-positive, alpha-beta T cell differentiation
regulation of neuron apoptotic process
ear development
thymic T cell selection
T-helper 2 cell differentiation
innate immune response
positive regulation of T cell differentiation
positive regulation of cell differentiation
negative regulation of fat cell differentiation
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
sympathetic nervous system development
thymus development
embryonic organ development
developmental growth
anatomical structure formation involved in morphogenesis
homeostasis of number of cells
negative regulation of inflammatory response
T cell receptor signaling pathway
regulation of histone H3-K4 methylation
positive regulation of protein kinase B signaling
parathyroid gland development
pharyngeal system development
uterus development
mesenchymal to epithelial transition
mast cell differentiation
ureteric bud formation
regulation of histone H3-K27 methylation
canonical Wnt signaling pathway involved in metanephric kidney development
cellular response to cytokine stimulus
cellular response to interleukin-4
otic vesicle development
cellular response to BMP stimulus
renal system development
positive regulation of ureteric bud formation
nephric duct morphogenesis
nephric duct formation
regulation of nephron tubule epithelial cell differentiation
interleukin-4 secretion
interferon-gamma secretion
lymphocyte migration
regulation of establishment of cell polarity
negative regulation of cell motility
negative regulation of endothelial cell apoptotic process
negative regulation of cell proliferation involved in mesonephros development
positive regulation of thyroid hormone generation
positive regulation of interleukin-5 secretion
positive regulation of interleukin-13 secretion
positive regulation of transcription regulatory region DNA binding
regulation of cellular response to X-ray
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
nucleic acid binding transcription factor activity
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
enhancer sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
interleukin-2 receptor binding
protein binding
transcription factor binding
zinc ion binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
protein dimerization activity
E-box binding
HMG box domain binding