62689

• Gene Symbol: Arhgef2
• Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 2
• Gene Aliases: AA408978, GEF, GEF-H1, GEFH1, LFP40, Lbcl1, Lfc, P40, mKIAA0651
• Chromosome Location: Chr.3: 88593114 - 88649532 on Build GRCm38
• UniGene ID: Mm.239329
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Arhgef2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001198911.1	NP_001185840.1	3	364
	NM_001198912.1	NP_001185841.1	2	226
	NM_001198913.1	NP_001185842.1	2	226
	NM_008487.3	NP_032513.3	2	236
GenBank mRNA	AB093254.1	-	2	309
	AF177032.1	-	2	203
	AK144972.1	-	3	345
	AK156379.1	-	2	217
	AK158232.1	-	3	429
	AK167628.1	-	2	190
	AK171223.1	-	2	185
	BC006589.1	-	2	157	3587800
	KC508090.1	-	2	212
	U28495.1	-	2	203
	X95761.1	-	2	94

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012079, XM_006232643, XM_006232648, XM_006232652, XM_008761152, and others.

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
immune system process
actin filament organization
negative regulation of microtubule depolymerization
cell cycle
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
positive regulation of NF-kappaB transcription factor activity
cell division
cellular response to muramyl dipeptide

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding
Rac GTPase binding