62714

• Gene Symbol: Lrp5
• Gene Name: low density lipoprotein receptor-related protein 5
• Gene Aliases: BMND1, HBM, LR3, LRP7, OPPG, mKIAA4142
• Chromosome Location: Chr.19: 3584825 - 3686564 on Build GRCm38
• UniGene ID: Mm.274581
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Lrp5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008513.3	NP_032539.2	2	349
GenBank mRNA	AF064984.1	-	2	339
	AF077847.1	-	2	227
	AK081025.1	-	2	349
	AK147068.1	-	2	342
	AK147231.1	-	2	347
	AK147330.1	-	2	347
	AK220186.1	-	2	302
	BC011374.1	-	2	331	3154246
	BC094610.1	-	2	338

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106321, XM_006230726, BC166786.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

gastrulation with mouth forming second
vasculature development
positive regulation of mesenchymal cell proliferation
osteoblast development
glucose catabolic process
endocytosis
multicellular organism development
cholesterol metabolic process
regulation of blood pressure
positive regulation of cell proliferation
anterior/posterior pattern specification
Wnt signaling pathway
positive regulation of osteoblast proliferation
somatic stem cell population maintenance
limb morphogenesis
extracellular matrix-cell signaling
cell migration involved in gastrulation
cholesterol homeostasis
embryonic digit morphogenesis
regulation of apoptotic process
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of fat cell differentiation
negative regulation of osteoblast differentiation
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
bone remodeling
regulation of bone remodeling
bone marrow development
positive regulation of sequence-specific DNA binding transcription factor activity
anatomical structure regression
retina morphogenesis in camera-type eye
canonical Wnt signaling pathway
bone development
bone morphogenesis
branching involved in mammary gland duct morphogenesis
mammary gland duct morphogenesis
adipose tissue development
cell-cell signaling involved in mammary gland development
regulation of canonical Wnt signaling pathway
regulation of insulin secretion involved in cellular response to glucose stimulus
retina vasculature morphogenesis in camera-type eye
retinal blood vessel morphogenesis
negative regulation of protein serine/threonine kinase activity
apoptotic process involved in patterning of blood vessels

Function(s)

protein binding
Wnt-protein binding
Wnt-activated receptor activity