62841

• Gene Symbol: Mcl1
• Gene Name: myeloid cell leukemia sequence 1
• Gene Aliases: AW556805, Mcl-1
• Chromosome Location: Chr.3: 95658368 - 95663179 on Build GRCm38
• UniGene ID: Mm.1639
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mcl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008562.3	NP_032588.1	2	875
GenBank mRNA	AK010424.1	-	1	50
	AK159504.1	-	2	787
	AK160594.1	-	1	47
	AK215970.1	-	1	100
	BC003839.1	-	2	804	3491015
	BC005427.1	-	2	797	3493739
	BC021638.1	-	2	814	4190996
	GU182318.1	-	3	601
	U35623.1	-	2	787

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_021846, AF144096, BC078835, AF115380.

Gene Ontology Categories:

Process(es)

apoptotic process
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cell differentiation
response to cytokine
regulation of apoptotic process
negative regulation of apoptotic process
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
BH domain binding
BH3 domain binding