62941

• Gene Symbol: Men1
• Gene Name: multiple endocrine neoplasia 1
• Gene Aliases: AW045611
• Chromosome Location: Chr.19: 6334979 - 6340894 on Build GRCm38
• UniGene ID: Mm.12917
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Men1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001168488.1	NP_001161960.1	2	476
	NM_001168489.1	NP_001161961.1	2	454
	NM_001168490.1	NP_001161962.1	1	790
	NM_008583.2	NP_032609.1	1	790
GenBank mRNA	AB023401.1	-	1	417
	AF016398.1	-	2	429
	AF072755.1	-	2	413
	AF109389.1	-	1	789
	AF130368.1	-	1	772
	AK133984.1	-	2	412
	AK154371.1	-	2	435
	AK164700.1	-	2	411
	AK170713.1	-	1	770
	BC006610.1	-	2	409
	BC036287.1	-	1	718	4189611
	CF170561.1	-	2	432
	CX568988.1	-	1	462

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019208, XM_006230772, XM_006230771, XM_006230769, XM_006230770, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
ossification
leukocyte homeostasis
negative regulation of protein phosphorylation
osteoblast fate commitment
osteoblast development
type B pancreatic cell differentiation
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
cell cycle arrest
negative regulation of cell proliferation
response to UV
embryo development
response to gamma radiation
negative regulation of cell-substrate adhesion
chromatin modification
histone methylation
hemopoiesis
positive regulation of transforming growth factor beta receptor signaling pathway
positive regulation of histone methylation
positive regulation of protein binding
regulation of activin receptor signaling pathway
histone lysine methylation
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of cell differentiation
negative regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JNK cascade
negative regulation of organ growth
embryonic skeletal system morphogenesis
negative regulation of epithelial cell proliferation
positive regulation of cell division
negative regulation of telomerase activity
palate development
maternal process involved in female pregnancy
regulation of type B pancreatic cell proliferation
response to transforming growth factor beta
negative regulation of cell cycle G1/S phase transition

Function(s)

four-way junction DNA binding
Y-form DNA binding
DNA binding
chromatin binding
double-stranded DNA binding
protein binding
histone-lysine N-methyltransferase activity
protein binding, bridging
sequence-specific DNA binding
transcription regulatory region DNA binding
protein N-terminus binding
R-SMAD binding