63134

• Gene Symbol: Met
• Gene Name: met proto-oncogene
• Gene Aliases: AI838057, HGF, HGFR, Par4, c-Met
• Chromosome Location: Chr.6: 17463349 - 17573980 on Build GRCm38
• UniGene ID: Mm.86844
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Met
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008591.2	NP_032617.2	13	2974
GenBank mRNA	BC117969.1	-	11	2618
	BC117970.1	-	11	2614
	CK332973.1	-	2	90
	Y00671.1	-	11	2619

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000245, NM_001127500, AK296974, J02958, AB209898, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
neuron migration
endothelial cell morphogenesis
liver development
placenta development
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
brain development
muscle organ development
skeletal muscle tissue development
positive regulation of gene expression
positive regulation of peptidyl-threonine phosphorylation
negative regulation of peptidyl-threonine phosphorylation
positive regulation of glucose transport
positive regulation of neuron projection development
muscle cell migration
myotube differentiation
phosphorylation
peptidyl-tyrosine phosphorylation
sperm motility
adult behavior
positive regulation of peptidyl-serine phosphorylation
glucose homeostasis
positive regulation of DNA replication
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
hepatocyte growth factor receptor signaling pathway
branching morphogenesis of an epithelial tube
positive regulation of dendrite morphogenesis
modulation of synaptic transmission
positive chemotaxis
myoblast proliferation
excitatory postsynaptic potential
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
semaphorin-plexin signaling pathway
negative regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of endothelial cell chemotaxis

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
hepatocyte growth factor-activated receptor activity
protein binding
ATP binding
beta-catenin binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein phosphatase binding
protein complex binding
phospholipase binding
phosphatidylinositol 3-kinase binding
protein heterodimerization activity