6314

• Gene Symbol: MCL1
• Gene Name: BCL2 family apoptosis regulator
• Gene Aliases: BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
• Chromosome Location: Chr.1: 150574551 - 150579738 on Build GRCh38
• UniGene ID: Hs.632486
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MCL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001197320.1	NP_001184249.1	4	1070
	NM_021960.4	NP_068779.1	3	1529
	NM_182763.2	NP_877495.1	2	1281
GenBank mRNA	AF118124.1	-	3	1370
	AK294462.1	-	4	1101
	AK300499.1	-	4	1175
	AK304775.1	-	4	1211
	BC017197.2	-	3	1375	3138465
	BC071897.1	-	3	1377	6586159
	L08246.1	-	3	1381

More Information

Gene Ontology Categories:

Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding