63359

• Gene Symbol: Nthl1
• Gene Name: nth (endonuclease III)-like 1 (E.coli)
• Gene Aliases: Nth1, Octs3
• Chromosome Location: Chr.17: 24632682 - 24638838 on Build GRCm38
• UniGene ID: Mm.148315
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nthl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008743.2	NP_032769.2	2, 3	420
GenBank mRNA	AB006812.1	-	2, 3	366
	AK033701.1	-	2, 3	1428
	BC138852.1	-	2, 3	383	8861874
	BC138855.1	-	2, 3	383	8861877
	BC145443.1	-	2, 3	292
	CX565655.1	-	2, 3	399
	Y09688.1	-	2, 3	392

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105728.

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
DNA repair
base-excision repair
base-excision repair, AP site formation
nucleotide-excision repair, DNA incision, 5'-to lesion
cellular response to DNA damage stimulus
metabolic process
mitophagy in response to mitochondrial depolarization

Function(s)

purine-specific mismatch base pair DNA N-glycosylase activity
DNA binding
double-stranded DNA binding
catalytic activity
DNA-(apurinic or apyrimidinic site) lyase activity
uracil DNA N-glycosylase activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
lyase activity
single-strand selective uracil DNA N-glycosylase activity
DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity
metal ion binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
nicotinamide riboside hydrolase activity
nicotinic acid riboside hydrolase activity
deoxyribonucleoside 5'-monophosphate N-glycosidase activity