63603

• Gene Symbol: Pdx1
• Gene Name: pancreatic and duodenal homeobox 1
• Gene Aliases: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
• Chromosome Location: Chr.5: 147270131 - 147275149 on Build GRCm38
• UniGene ID: Mm.389714
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdx1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008814.3	NP_032840.1	2	731
GenBank mRNA	AK020261.1	-		736
	BC103572.1	-	2	731	40045668
	BC103581.1	-	2	731	40045664
	BC103582.1	-	2	731	40045666
	BC105642.1	-	2	731	40045665
	X74342.1	-	2	902

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: AF049893.
This siRNA also targets the following transcripts in Rat: NM_022852, U04833.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
liver development
type B pancreatic cell differentiation
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
smoothened signaling pathway
nitric oxide mediated signal transduction
multicellular organism development
positive regulation of cell proliferation
negative regulation of cell proliferation
response to glucose
regulation of gene expression
positive regulation of cell death
morphogenesis of embryonic epithelium
insulin secretion
cell differentiation
pancreas development
exocrine pancreas development
endocrine pancreas development
positive regulation of insulin secretion
positive regulation of insulin secretion involved in cellular response to glucose stimulus
regulation of cell proliferation
glucose homeostasis
positive regulation of DNA binding
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
stem cell differentiation
detection of glucose
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of type B pancreatic cell apoptotic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
protein complex binding
sequence-specific DNA binding
protein heterodimerization activity