63652

• Gene Symbol: Serpine1
• Gene Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
• Gene Aliases: PAI-1, PAI1, Planh1
• Chromosome Location: Chr.5: 137061504 - 137072272 on Build GRCm38
• UniGene ID: Mm.250422
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Serpine1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008871.2	NP_032897.2	3, 4	647
GenBank mRNA	BC054091.1	-	3, 4	644	30021925
	GQ872458.1	-	2, 3	502
	GQ872459.1	-	2, 3	502
	M33960.1	-	3, 4	633

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

female gonad development
negative regulation of peptidase activity
regulation of receptor activity
positive regulation of gene expression
negative regulation of gene expression
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
negative regulation of smooth muscle cell migration
positive regulation of blood coagulation
negative regulation of cell migration
positive regulation of interleukin-8 production
negative regulation of cell adhesion mediated by integrin
positive regulation of leukotriene production involved in inflammatory response
cellular response to drug
wound healing
regulation of cell proliferation
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of fibroblast proliferation
positive regulation of receptor-mediated endocytosis
positive regulation of inflammatory response
positive regulation of coagulation
defense response to Gram-negative bacterium
positive regulation of keratinocyte migration
negative regulation of fibrinolysis
negative regulation of vascular wound healing
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to transforming growth factor beta stimulus
positive regulation of monocyte chemotaxis
positive regulation of calcium ion import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of smooth muscle cell-matrix adhesion
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding
peptidase inhibitor activity