63869

• Gene Symbol: Ppm1a
• Gene Name: protein phosphatase 1A, magnesium dependent, alpha isoform
• Gene Aliases: 2310003C21Rik, 2900017D14Rik, AI427932, AU017636, MMPa-2, MPPa-1
• Chromosome Location: Chr.12: 72761211 - 72799822 on Build GRCm38
• UniGene ID: Mm.261045
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ppm1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008910.3	NP_032936.1	2	647
GenBank mRNA	AF259672.1	-	1	206
	AF259673.1	-	1	206
	AF369981.1	-	1	216
	AK076054.1	-	2	544
	AK191727.1	-	1	229
	AK204448.1	-	1	229
	BC008595.1	-	2	254	3581897
	D28117.1	-	2	323

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_021003, NM_177952, NM_177951, BC063243, AB451371, and others.
This siRNA also targets the following transcripts in Rat: NM_017038, XM_006240195, XM_006240194, XM_006240193, J04503.

Gene Ontology Categories:

Process(es)

protein dephosphorylation
N-terminal protein myristoylation
negative regulation of SMAD protein complex assembly
Wnt signaling pathway
dephosphorylation
positive regulation of Wnt signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
peptidyl-threonine dephosphorylation
negative regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription, DNA-templated
positive regulation of protein export from nucleus
cellular response to transforming growth factor beta stimulus

Function(s)

magnesium ion binding
catalytic activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein C-terminus binding
hydrolase activity
manganese ion binding
calmodulin-dependent protein phosphatase activity
metal ion binding
R-SMAD binding