64008

• Gene Symbol: Ptgis
• Gene Name: prostaglandin I2 (prostacyclin) synthase
• Gene Aliases: Cyp8, Cyp8a1, Pgis
• Chromosome Location: Chr.2: 167203194 - 167252127 on Build GRCm38
• UniGene ID: Mm.2339
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptgis
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008968.3	NP_032994.1	10	1726
GenBank mRNA	AB001607.1	-	10	1644
	AK076585.1	-	10	1727
	BC062151.1	-	10	1733	6512164

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031557, BC061814.

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
response to hypoxia
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
prostaglandin metabolic process
embryo implantation
negative regulation of NF-kappaB transcription factor activity
positive regulation of peroxisome proliferator activated receptor signaling pathway
regulation of apoptotic process
negative regulation of nitric oxide biosynthetic process
positive regulation of angiogenesis
decidualization
negative regulation of inflammatory response
oxidation-reduction process
cellular response to hypoxia
apoptotic signaling pathway
positive regulation of execution phase of apoptosis

Function(s)

monooxygenase activity
iron ion binding
prostaglandin-I synthase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
isomerase activity
heme binding
metal ion binding