6410

• Gene Symbol: GPER1
• Gene Name: G protein-coupled estrogen receptor 1
• Gene Aliases: CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR, mER
• Chromosome Location: Chr.7: 1086807 - 1093815 on Build GRCh38
• UniGene ID: Hs.20961
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GPER1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039966.1	NP_001035055.1	3	1306
	NM_001098201.1	NP_001091671.1	2	979
	NM_001505.2	NP_001496.1	2	1182
GenBank mRNA	AB451427.1	-	1	422
	AF015257.1	-	2	1113
	AK289588.1	-	2	953
	BC011634.1	-	1	513	4079700
	BC082766.1	-	1	523	5419168
	CR541655.1	-	1	422
	CR541741.1	-	1	422
	U63917.1	-	2	926
	X98510.1	-	1	595
	Y08162.1	-	1	422

More Information

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
negative regulation of leukocyte activation
inflammatory response
cell cycle
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
negative regulation of cell cycle process
positive regulation of phosphatidylinositol 3-kinase signaling
neuronal action potential
apoptotic chromosome condensation
nuclear fragmentation involved in apoptotic nuclear change
positive regulation of cell migration
intracellular steroid hormone receptor signaling pathway
positive regulation of cAMP biosynthetic process
mineralocorticoid receptor signaling pathway
positive regulation of insulin secretion
positive regulation of inositol trisphosphate biosynthetic process
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
steroid hormone mediated signaling pathway
positive regulation of MAPK cascade
innate immune response
negative regulation of fat cell differentiation
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
positive regulation of neurogenesis
negative regulation of DNA metabolic process
negative regulation of lipid biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
negative regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of uterine smooth muscle contraction
negative regulation of cell cycle arrest
cellular response to glucose stimulus
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
cellular response to mineralocorticoid stimulus
cellular response to estradiol stimulus
positive regulation of establishment of protein localization to plasma membrane
positive regulation of release of cytochrome c from mitochondria
negative regulation of vascular smooth muscle cell proliferation
positive regulation of endothelial cell apoptotic process
positive regulation of cardiac vascular smooth muscle cell differentiation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

chromatin binding
G-protein coupled receptor activity
steroid binding
protein binding
drug binding
mineralocorticoid receptor activity
estrogen receptor activity
steroid hormone binding