64354

• Gene Symbol: Map2k4
• Gene Name: mitogen-activated protein kinase kinase 4
• Gene Aliases: JNKK1, MEK4, MKK4, PRKMK4, Sek1, Serk1
• Chromosome Location: Chr.11: 65688244 - 65788354 on Build GRCm38
• UniGene ID: Mm.412922
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map2k4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009157.4	NP_033183.1	3	308
GenBank mRNA	AK036928.1	-	3	312
	AK044534.1	-	3	300
	AK044698.1	-	3	300
	AK139777.1	-	4	330
	AK187893.1	-	3	167
	BC029833.1	-	1	59	3962163
	U18310.1	-	3	283

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001281435, NM_003010, AK313053, AK294923, AK316100, and others.
This siRNA also targets the following transcripts in Rat: NM_001030023, AY880882, KC795688.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of protein phosphorylation
protein phosphorylation
apoptotic process
JNK cascade
activation of JUN kinase activity
phosphorylation
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of DNA replication
positive regulation of nitric-oxide synthase biosynthetic process
cell growth involved in cardiac muscle cell development

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
JUN kinase kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase kinase kinase binding