64501

• Gene Symbol: Nr1h4
• Gene Name: nuclear receptor subfamily 1, group H, member 4
• Gene Aliases: AI957360, Fxr, HRR1, RIP14, Rxrip14
• Chromosome Location: Chr.10: 89454234 - 89533645 on Build GRCm38
• UniGene ID: Mm.3095
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr1h4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001163504.1	NP_001156976.1	5	925
	NM_001163700.1	NP_001157172.1	4	721
	NM_009108.2	NP_033134.2	4	709
GenBank mRNA	AK002513.1	-	4	707
	AK132255.1	-	4	701
	BC015261.1	-	4	680	4241705
	U09416.1	-	4	678
	U09417.1	-	5	889
	U09418.1	-	5	886

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_021745, XM_008765261, XM_008765262, XM_008765260, U18374, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
nitrogen catabolite activation of transcription from RNA polymerase II promoter
regulation of carbohydrate metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Notch signaling pathway
bile acid metabolic process
intracellular receptor signaling pathway
regulation of urea metabolic process
intracellular bile acid receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription from RNA polymerase II promoter
negative regulation of bile acid biosynthetic process
cellular response to organonitrogen compound
cellular response to bile acid
positive regulation of glutamate metabolic process
positive regulation of ammonia assimilation cycle

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
thyroid hormone receptor activity
zinc ion binding
bile acid binding
bile acid receptor activity
peptide binding
sequence-specific DNA binding
metal ion binding
retinoid X receptor binding
chenodeoxycholic acid binding