6472

• Gene Symbol: CRK
• Gene Name: CRK proto-oncogene, adaptor protein
• Gene Aliases: CRKII, p38
• Chromosome Location: Chr.17: 1421353 - 1456267 on Build GRCh38
• UniGene ID: Hs.461896
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CRK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005206.4	NP_005197.3	2	527
	NM_016823.3	NP_058431.2	2	527
GenBank mRNA	AK291060.1	-	2	492
	BC001718.1	-	2	479	3353237
	BC008506.1	-	2	510	3452137
	BC009837.1	-	2	492	4040536
	BT007277.1	-	2	377
	D10656.1	-	2	482
	KU177996.1	-	2	377
	KU177997.1	-	2	377

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019302, XM_006246913, D44481, FQ210506.
This siRNA also targets the following transcripts in Mouse: NM_001277219, NM_133656, BC012216, AK152549, AK052795, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
regulation of transcription from RNA polymerase II promoter
regulation of actin cytoskeleton organization
regulation of Rac protein signal transduction
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

SH3/SH2 adaptor activity
protein binding
SH2 domain binding
protein phosphorylated amino acid binding
ephrin receptor binding