65117

• Gene Symbol: Top2b
• Gene Name: topoisomerase (DNA) II beta
• Gene Aliases: D230016L12Rik, Top-2
• Chromosome Location: Chr.14: 16365206 - 16430787 on Build GRCm38
• UniGene ID: Mm.130362
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Top2b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009409.2	NP_033435.2	18	2611
GenBank mRNA	BC041106.1	-	18	2631	5368508
	BC054541.1	-	18	2611	6406462
	D38046.1	-	18	2184

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001068, M27504, AB208879, X68060, AK307450, and others.
This siRNA also targets the following transcripts in Rat: NM_001100858, AB262979.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
neuron migration
DNA metabolic process
DNA topological change
DNA unwinding involved in DNA replication
axonogenesis
forebrain development
mitotic DNA integrity checkpoint

Function(s)

nucleotide binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA binding, bending
isomerase activity
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity