65412

• Gene Symbol: Zap70
• Gene Name: zeta-chain (TCR) associated protein kinase
• Gene Aliases: Srk, ZAP-70, mrtle, mur
• Chromosome Location: Chr.1: 36761798 - 36782821 on Build GRCm38
• UniGene ID: Mm.8038
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Zap70
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001289765.1	NP_001276694.1	3	649
	NM_001289766.1	NP_001276695.1	3	614
	NM_009539.3	NP_033565.2	3	606
GenBank mRNA	AK039883.1	-	3	543
	AK089056.1	-	3	579
	BC029727.1	-	3	564	4925739
	U04379.1	-	3	560
	U77667.1	-	2	452

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001079, L05148, AK310628, AK303341, BC053878, and others.
This siRNA also targets the following transcripts in Rat: NM_001012002, XM_003752219, XM_006244761, XM_008766998, BC089855.

Gene Ontology Categories:

Process(es)

immune system process
protein phosphorylation
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
beta selection
positive thymic T cell selection
negative thymic T cell selection
thymic T cell selection
innate immune response
positive regulation of T cell differentiation
positive regulation of alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
protein autophosphorylation
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway

Function(s)

nucleotide binding
phosphotyrosine binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups