6573

• Gene Symbol: GLI2
• Gene Name: GLI family zinc finger 2
• Gene Aliases: CJS, HPE9, PHS2, THP1, THP2
• Chromosome Location: Chr.2: 120797291 - 120992653 on Build GRCh38
• UniGene ID: Hs.111867
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GLI2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005270.4	NP_005261.2	8	1306
	XM_006712422.2	XP_006712485.1	8	1255
	XM_011510969.2	XP_011509271.2	8	1938
	XM_011510970.2	XP_011509272.1	8	2949
	XM_011510971.2	XP_011509273.1	8	2199
	XM_011510972.2	XP_011509274.2	8	1336
	XM_011510973.2	XP_011509275.1	7	1087
	XM_011510974.2	XP_011509276.1	7	1095
	XM_017003818.1	XP_016859307.1	8	1887
GenBank mRNA	AB007295.1	-	5	863
	AB007296.1	-	5	812
	AB007297.1	-	5	863
	AB007298.1	-	5	812
	BC111410.1	-	8	1250
	D14827.1	-	5	812
	D14828.1	-	4	708
	DQ004396.1	-	7	1095
	DQ086814.1	-	8	1276

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107169, XM_008769455.
This siRNA also targets the following transcripts in Mouse: NM_001081125, AM262742, AM262744, AM262741, X99104, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
in utero embryonic development
kidney development
chondrocyte differentiation
osteoblast development
transcription from RNA polymerase II promoter
smoothened signaling pathway
pattern specification process
axon guidance
ventral midline development
hindgut morphogenesis
heart development
cell proliferation
regulation of smoothened signaling pathway
response to mechanical stimulus
anterior/posterior pattern specification
proximal/distal pattern formation
floor plate formation
spinal cord dorsal/ventral patterning
ventral spinal cord development
cerebellar cortex morphogenesis
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
spinal cord ventral commissure morphogenesis
pituitary gland development
lung development
mammary gland development
hindbrain development
negative regulation of chondrocyte differentiation
positive regulation of T cell differentiation in thymus
tube development
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
negative regulation of apoptotic process
positive regulation of neuron differentiation
positive regulation of DNA replication
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract development
developmental growth
neuron development
branching morphogenesis of an epithelial tube
notochord regression
prostatic bud formation
mammary gland duct morphogenesis
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
cellular response to organic cyclic compound
cochlea morphogenesis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding