66144

• Gene Symbol: Socs1
• Gene Name: suppressor of cytokine signaling 1
• Gene Aliases: Cish1, Cish7, JAB, SOCS-1, SSI-1
• Chromosome Location: Chr.16: 10783808 - 10785536 on Build GRCm38
• UniGene ID: Mm.130
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Socs1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271603.1	NP_001258532.1	2	1241
	NM_009896.2	NP_034026.1	2	1121
GenBank mRNA	AB000677.1	-	1	965
	AF120490.1	-	2	1094
	AF180302.1	-	2	1099
	AK028632.1	-		1122
	AK154706.1	-		1138
	U88325.1	-	2	1083

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_145879.

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
negative regulation of protein kinase activity
JAK-STAT cascade
negative regulation of signal transduction
regulation of activation of JAK2 kinase activity
cytokine-mediated signaling pathway
intracellular signal transduction
regulation of growth
regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of catalytic activity
fat cell differentiation
regulation of JAK-STAT cascade
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
regulation of cytokine secretion
regulation of interferon-gamma-mediated signaling pathway
cellular response to amino acid stimulus

Function(s)

protein kinase inhibitor activity
insulin-like growth factor receptor binding
protein binding
kinase inhibitor activity
protein kinase binding