66310

Gene Symbol:

Cyp11b1 Cyp11b2

Gene Name:

cytochrome P450, family 11, subfamily b, polypeptide 1

cytochrome P450, family 11, subfamily b, polypeptide 2

Gene Aliases:

AA389061, CPN1, Cyp11b, Cyp11b-1, FHI

Cpn2, Cyp11b, Cyp11b-2

Chromosome Location:

Chr.15: 74834892 - 74841643 on Build GRCm38

Chromosome Location:

Chr.15: 74851010 - 74856318 on Build GRCm38

UniGene ID:

Mm.322606

Mm.377079

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Cyp11b1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033229.3	NP_001028401.2	1	182
GenBank mRNA	AK142439.1	-	1	159
	AK163083.1	-	1	158
	AK168839.1	-	1	159
	BC139248.1	-	1	182	8862270
	BC139250.1	-	1	182	8862272

Gene Symbol: Cyp11b2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009991.3	NP_034121.3	1	238
GenBank mRNA	BC116908.1	-	1	238	40126227
	BC119321.1	-	1	238	8734070

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012538, NM_181824, NM_012537, XM_008765623, XM_008765541, and others.

Gene Ontology Categories:

Process(es)

regulation of blood volume by renal aldosterone
C21-steroid hormone biosynthetic process
glucocorticoid biosynthetic process
aldosterone biosynthetic process
potassium ion homeostasis
sodium ion homeostasis
oxidation-reduction process
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
steroid biosynthetic process
regulation of blood pressure
cortisol biosynthetic process
drinking behavior
positive regulation of blood pressure
ion homeostasis

Function(s)

steroid 11-beta-monooxygenase activity
heme binding
corticosterone 18-monooxygenase activity
monooxygenase activity
iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding