66336

• Gene Symbol: Cln3
• Gene Name: ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
• Gene Aliases: AI323623
• Chromosome Location: Chr.7: 126571400 - 126585817 on Build GRCm38
• UniGene ID: Mm.268930
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cln3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001146311.1	NP_001139783.1	12, 13	1132
	NM_009907.3	NP_034037.3	10, 11	1020
GenBank mRNA	AK078976.1	-	10, 11	1004
	AK134036.1	-	13, 14	1655
	AK184160.1	-	2, 3	83
	AK217815.1	-	2, 3	82
	BC058753.1	-	11, 12	956	6477909
	BC060306.1	-	9, 10	902	5250894
	BC080759.1	-	11, 12	914	5353776
	U47106.1	-	10, 11	970
	U68064.1	-	10, 11	990
	U92811.1	-	10, 11	939

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000086, NM_001042432, BC111068, AF015598, BC002394, and others.
This siRNA also targets the following transcripts in Rat: NM_001006971, XM_008759874, XM_008759871, XM_008759872, XM_008759875, and others.

Panther Classification:

Molecular Function -

membrane trafficking regulatory protein

Gene Ontology Categories:

Process(es)

action potential
globoside metabolic process
positive regulation of protein phosphorylation
cellular amino acid metabolic process
ceramide metabolic process
glucosylceramide metabolic process
galactosylceramide metabolic process
sphingomyelin metabolic process
transport
amino acid transport
endocytosis
receptor-mediated endocytosis
vacuolar transport
lysosome organization
lysosomal lumen acidification
associative learning
regulation of gene expression
arginine transport
macroautophagy
negative regulation of macroautophagy
cell migration
protein processing
actin cytoskeleton organization
ionotropic glutamate receptor signaling pathway
lysosomal lumen pH elevation
neurotransmitter metabolic process
amyloid precursor protein catabolic process
negative regulation of apoptotic process
negative regulation of catalytic activity
negative regulation of neuron apoptotic process
negative regulation of proteolysis
vesicle transport along microtubule
neuromuscular process controlling balance
regulation of cytosolic calcium ion concentration
regulation of filopodium assembly
membrane organization
protein localization to membrane
protein localization to plasma membrane
autophagosome maturation

Function(s)

protein binding
calcium-dependent protein binding