66554

• Gene Symbol: Drd2
• Gene Name: dopamine receptor D2
• Gene Aliases: D2R, Drd-2
• Chromosome Location: Chr.9: 49340428 - 49408174 on Build GRCm38
• UniGene ID: Mm.41970
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Drd2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010077.2	NP_034207.2	3	413
GenBank mRNA	BC105663.1	-	3	413	40046665
	BC105664.1	-	3	413	40046668
	BC105665.1	-	3	413	40046660
	BC105666.1	-	3	413	40046662
	X55674.1	-	3	448

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000795, NM_016574, AB451480, X51645, AK308777, and others.
This siRNA also targets the following transcripts in Rat: NM_012547, XM_006242979, XM_008766190, XM_008766191, X56065, and others.

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

temperature homeostasis
response to hypoxia
synaptic transmission, dopaminergic
startle response
response to amphetamine
neurological system process involved in regulation of systemic arterial blood pressure
regulation of heart rate
regulation of sodium ion transport
G-protein coupled receptor internalization
positive regulation of neuroblast proliferation
positive regulation of receptor internalization
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
adenylate cyclase-inhibiting dopamine receptor signaling pathway
dopamine receptor signaling pathway
chemical synaptic transmission
neuron-neuron synaptic transmission
axonogenesis
sensory perception of smell
long-term memory
grooming behavior
locomotory behavior
adult walking behavior
feeding behavior
protein localization
negative regulation of cell proliferation
associative learning
visual learning
response to light stimulus
response to toxic substance
regulation of dopamine secretion
Wnt signaling pathway
cerebral cortex GABAergic interneuron migration
adenohypophysis development
negative regulation of cell migration
peristalsis
adult behavior
regulation of cAMP metabolic process
forebrain development
auditory behavior
activation of protein kinase activity
regulation of synaptic transmission, GABAergic
positive regulation of cytokinesis
circadian regulation of gene expression
negative regulation of dopamine secretion
response to histamine
intracellular signal transduction
positive regulation of urine volume
positive regulation of renal sodium excretion
positive regulation of multicellular organism growth
response to cocaine
negative regulation of circadian sleep/wake cycle, sleep
dopamine metabolic process
response to drug
regulation of potassium ion transport
response to morphine
regulation of MAPK cascade
pigmentation
regulation of phosphoprotein phosphatase activity
positive regulation of G-protein coupled receptor protein signaling pathway
negative regulation of blood pressure
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol metabolic process
negative regulation of insulin secretion
acid secretion
behavioral response to cocaine
behavioral response to ethanol
regulation of long-term neuronal synaptic plasticity
branching morphogenesis of a nerve
arachidonic acid secretion
negative regulation of protein secretion
modulation of synaptic transmission
release of sequestered calcium ion into cytosol
negative regulation of cytosolic calcium ion concentration
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
regulation of dopamine uptake involved in synaptic transmission
positive regulation of dopamine uptake involved in synaptic transmission
regulation of synapse structural plasticity
negative regulation of protein kinase B signaling
negative regulation of synaptic transmission, glutamatergic
positive regulation of growth hormone secretion
prepulse inhibition
phospholipase C-activating dopamine receptor signaling pathway
negative regulation of dopamine receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
regulation of locomotion involved in locomotory behavior
positive regulation of glial cell-derived neurotrophic factor secretion
positive regulation of long-term synaptic potentiation
negative regulation of voltage-gated calcium channel activity

Function(s)

dopamine neurotransmitter receptor activity, coupled via Gi/Go
signal transducer activity
G-protein coupled receptor activity
dopamine neurotransmitter receptor activity
receptor binding
drug binding
dopamine binding
ionotropic glutamate receptor binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity