66608

• Gene Symbol: Esr2
• Gene Name: estrogen receptor 2 (beta)
• Gene Aliases: ER[b], ERbeta, Estrb
• Chromosome Location: Chr.12: 76120419 - 76177259 on Build GRCm38
• UniGene ID: Mm.2561
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Esr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010157.3	NP_034287.3	3	914
	NM_207707.1	NP_997590.1	3	914
GenBank mRNA	AK054290.1	-	3	912
	AK054301.1	-	3	915
	AK054413.1	-	3	915
	AY054413.1	-	2	375
	BC141075.1	-	2	616	9055687
	BC145329.1	-	2	616	9053885
	U81451.1	-	2	386

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001214902, NM_001437, NM_001214903, NM_001040275, NM_001271876, and others.
This siRNA also targets the following transcripts in Rat: NM_012754, XM_006240221, AB012721, AF042060, AB190770, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovarian follicle development
behavioral fear response
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
brain development
learning or memory
negative regulation of cell proliferation
hormone-mediated apoptotic signaling pathway
intracellular steroid hormone receptor signaling pathway
intracellular estrogen receptor signaling pathway
response to testosterone
regulation of cell proliferation
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
regulation of neuron apoptotic process
estrous cycle
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of behavior
negative regulation of smooth muscle cell proliferation
negative regulation of epithelial cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
Sertoli cell proliferation
uterus development
vagina development
negative regulation of cell death
prostate gland epithelium morphogenesis
epithelial cell maturation involved in prostate gland development
negative regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of neuron death
negative regulation of feeding behavior
negative regulation of reactive oxygen species metabolic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
steroid binding
protein binding
drug binding
zinc ion binding
lipid binding
enzyme binding
estrogen receptor activity
estrogen response element binding
hormone binding
peroxisome proliferator activated receptor binding
sequence-specific DNA binding
metal ion binding
estradiol binding
steroid hormone binding