66775

• Gene Symbol: Epas1
• Gene Name: endothelial PAS domain protein 1
• Gene Aliases: HIF-2alpha, HIF2A, HLF, HRF, MOP2, bHLHe73
• Chromosome Location: Chr.17: 86753864 - 86833410 on Build GRCm38
• UniGene ID: Mm.1415
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Epas1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010137.3	NP_034267.3	16	3362
GenBank mRNA	AF045160.1	-	16	3126
	D89787.1	-	16	3325

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

angiogenesis
response to hypoxia
embryonic placenta development
blood vessel remodeling
regulation of heart rate
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
response to oxidative stress
mitochondrion organization
signal transduction
multicellular organism development
visual perception
hemopoiesis
cell differentiation
erythrocyte differentiation
lung development
norepinephrine metabolic process
surfactant homeostasis
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter
cell maturation
myoblast fate commitment
iron ion homeostasis
cellular response to hypoxia

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
protein binding
transcription factor binding
histone acetyltransferase binding
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity