67175

• Gene Symbol: Gck
• Gene Name: glucokinase
• Gene Aliases: GLK, Gk, Gls006, HK4, HKIV, HXKP, Hlb62, MODY2
• Chromosome Location: Chr.11: 5900816 - 5950081 on Build GRCm38
• UniGene ID: Mm.220358
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gck
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001287386.1	NP_001274315.1	2	213
	NM_010292.5	NP_034422.2	2	571
GenBank mRNA	AK142698.1	-	2	212
	BC011139.1	-	2	202	4195943
	L38990.1	-	2	89
	M58755.1	-	2	567

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012565, NM_001270849, NM_001270850, XM_006251179, KJ026953, and others.

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

cellular glucose homeostasis
carbohydrate metabolic process
glycogen biosynthetic process
fructose 2,6-bisphosphate metabolic process
glucose metabolic process
glycolytic process
NADP metabolic process
positive regulation of cytosolic calcium ion concentration
phosphorylation
second-messenger-mediated signaling
positive regulation of insulin secretion
negative regulation of epinephrine secretion
cellular response to insulin stimulus
cellular response to glucose starvation
positive regulation of phosphorylation
glucose homeostasis
regulation of potassium ion transport
cellular response to leptin stimulus
negative regulation of gluconeogenesis
positive regulation of glycogen biosynthetic process
positive regulation of glycolytic process
carbohydrate phosphorylation
regulation of insulin secretion
glucose 6-phosphate metabolic process
detection of glucose
lipid homeostasis
calcium ion import

Function(s)

nucleotide binding
magnesium ion binding
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
protein phosphatase binding
ADP binding