67252

• Gene Symbol: Hdac5
• Gene Name: histone deacetylase 5
• Gene Aliases: AI426555, Hdac4, mHDA1, mKIAA0600
• Chromosome Location: Chr.11: 102195747 - 102230186 on Build GRCm38
• UniGene ID: Mm.22665
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001077696.1	NP_001071164.1	6	909
	NM_001284248.1	NP_001271177.1	8	1421
	NM_001284249.1	NP_001271178.1	7	1018
	NM_001284250.1	NP_001271179.1	6	906
	NM_010412.3	NP_034542.3	6	906
GenBank mRNA	AF006602.2	-	5	622
	AF207748.1	-	5	541
	AK145972.1	-	6	872
	AK146483.1	-	6	845
	AK155335.1	-	6	880
	AK156008.1	-	3	1157
	AK157159.1	-	3	1157
	BC049926.1	-	6	842
	BC058554.1	-	8	1373
	BC060609.1	-	5	700	5720438

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053450, AF321133.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein deacetylation
inflammatory response
nervous system development
heart development
negative regulation of gene expression
regulation of myotube differentiation
negative regulation of myotube differentiation
chromatin modification
histone deacetylation
B cell differentiation
multicellular organismal response to stress
regulation of gene expression, epigenetic
B cell activation
response to cocaine
response to drug
regulation of protein binding
negative regulation of osteoblast differentiation
negative regulation of striated muscle tissue development
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of skeletal muscle fiber development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of striated muscle cell differentiation
renal tubule morphogenesis
cellular response to fluid shear stress
negative regulation of cell migration involved in sprouting angiogenesis
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation

Function(s)

RNA polymerase III transcription factor binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein kinase C binding
protein binding
transcription factor binding
hydrolase activity
protein kinase binding
histone deacetylase activity (H3-K14 specific)
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase binding
transcription regulatory region DNA binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
repressing transcription factor binding
NAD-dependent histone deacetylase activity (H3-K18 specific)