67634

• Gene Symbol: Jun
• Gene Name: jun proto-oncogene
• Gene Aliases: AP-1, Junc, c-jun
• Chromosome Location: Chr.4: 95049036 - 95052222 on Build GRCm38
• UniGene ID: Mm.275071
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Jun
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010591.2	NP_034721.1	1	1811
GenBank mRNA	AK132019.1	-	1	1786
	AK133722.1	-	1	1792
	AK133867.1	-	1	1794
	AK135023.1	-	1	1790
	AK140911.1	-	1	1786
	AK159196.1	-	1	1786
	BC002081.1	-	1	954	3493248
	BC021888.1	-	1	1745	3156091
	BC032086.1	-	1	1279
	BC055887.1	-	1	1888
	BC094032.1	-	2	1673	4936392
	J04115.1	-	1	1776
	X12740.1	-	1	1474
	X12761.1	-	1	1214

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002228, CR541724, BC006175, BC009874, BT019759, and others.
This siRNA also targets the following transcripts in Rat: NM_021835, BC078738, X17163.

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
microglial cell activation
release of cytochrome c from mitochondria
liver development
positive regulation of endothelial cell proliferation
outflow tract morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
learning
positive regulation of cell proliferation
negative regulation of cell proliferation
response to radiation
cellular process
monocyte differentiation
axon regeneration
negative regulation of protein autophosphorylation
response to lipopolysaccharide
cellular response to hormone stimulus
response to cytokine
leading edge cell differentiation
response to muscle stretch
response to drug
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
negative regulation by host of viral transcription
positive regulation by host of viral transcription
positive regulation of cell differentiation
positive regulation of monocyte differentiation
positive regulation of DNA replication
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
cellular response to potassium ion starvation
response to cAMP
regulation of cell cycle
membrane depolarization
SMAD protein signal transduction
cellular response to calcium ion
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of DNA-templated transcription, initiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
GTPase activator activity
protein binding
transcription factor binding
enzyme binding
cAMP response element binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
protein heterodimerization activity
R-SMAD binding
HMG box domain binding