67725

• Gene Symbol: Itpr1
• Gene Name: inositol 1,4,5-trisphosphate receptor 1
• Gene Aliases: D6Pas2, ENSMUSG00000072853, Gm10429, IP3R1, InsP3R, Ip3r, Itpr-1, P400, Pcp-1, Pcp1, opt
• Chromosome Location: Chr.6: 108213083 - 108551116 on Build GRCm38
• UniGene ID: Mm.227912
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Itpr1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010585.5	NP_034715.3	8	901
GenBank mRNA	AK047719.1	-	8	902
	AK049015.1	-	5	515
	AK137477.1	-	8	903
	X15373.1	-	8	879

More Information

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

response to hypoxia
transport
ion transport
calcium ion transport
apoptotic process
positive regulation of cytosolic calcium ion concentration
post-embryonic development
endoplasmic reticulum calcium ion homeostasis
inositol phosphate-mediated signaling
negative regulation of calcium-mediated signaling
voluntary musculoskeletal movement
release of sequestered calcium ion into cytosol
positive regulation of calcium ion transport
transmembrane transport
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
calcium ion transmembrane transport
cellular response to cAMP
negative regulation of neuron death

Function(s)

ion channel activity
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
calcium channel activity
protein binding
protein C-terminus binding
calcium-release channel activity
calcium channel inhibitor activity
protein phosphatase binding
protein complex binding
phosphatidylinositol binding