67807

• Gene Symbol: Inpp5d
• Gene Name: inositol polyphosphate-5-phosphatase D
• Gene Aliases: SHIP, SHIP-1, SHIP1, SIP-145, p150Ship, s-SHIP
• Chromosome Location: Chr.1: 87620312 - 87720510 on Build GRCm38
• UniGene ID: Mm.15105
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Inpp5d
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001110192.2	NP_001103662.1	10	1304
	NM_001110193.2	NP_001103663.1	10	1307
	NM_010566.3	NP_034696.2	10	1307
GenBank mRNA	AF125996.1	-	10	1220
	AF184912.1	-	5	500
	AF184913.1	-	5	500
	AF228679.1	-	10	1218
	AK143560.1	-	10	1244
	BC108328.1	-	10	1180	30839591
	U39203.1	-	10	1256
	U51742.1	-	10	1218
	U52044.1	-	10	1240

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001017915, NM_005541, U84400, U50041, U57650, and others.

Gene Ontology Categories:

Process(es)

immune system process
apoptotic process
negative regulation of cell proliferation
determination of adult lifespan
negative regulation of signal transduction
immunoglobulin mediated immune response
dephosphorylation
negative regulation of granulocyte differentiation
negative regulation of B cell proliferation
intracellular signal transduction
positive regulation of apoptotic process
negative regulation of interleukin-6 biosynthetic process
positive regulation of B cell differentiation
positive regulation of lymphocyte differentiation
positive regulation of erythrocyte differentiation
negative regulation of monocyte differentiation
negative regulation of neutrophil differentiation
negative regulation of osteoclast differentiation
negative regulation of bone resorption
phosphatidylinositol dephosphorylation
negative regulation of immune response
negative regulation of B cell activation

Function(s)

inositol-polyphosphate 5-phosphatase activity
protein binding
hydrolase activity
SH3 domain binding
inositol-4,5-bisphosphate 5-phosphatase activity
phosphatidylinositol trisphosphate phosphatase activity
PTB domain binding