68231

• Gene Symbol: Nedd4
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4
• Gene Aliases: AA959633, AL023035, AU019897, E430025J12Rik, Nedd4-1, Nedd4a, mKIAA0093
• Chromosome Location: Chr.9: 72662347 - 72749851 on Build GRCm38
• UniGene ID: Mm.279923
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nedd4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010890.3	NP_035020.2	8	776
GenBank mRNA	AK050517.1	-	8	642
	AK054450.1	-	7	1782
	AK088620.1	-	8	680
	AK088767.1	-	8	689
	AK122203.1	-	8	619
	AK133838.1	-	8	689
	AK144240.1	-	8	690
	AK160570.1	-	8	641
	AK205844.1	-	3	134
	BC138813.1	-	8	654	8861835
	D85414.1	-	8	776
	U96635.1	-	8	847

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_006154, AK307541, D42055, BC144284, AL833300, and others.
This siRNA also targets the following transcripts in Rat: NM_012986, XM_008766214, CK365888, U50842.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
adaptive immune response
outflow tract morphogenesis
endocardial cushion development
protein monoubiquitination
nervous system development
neuromuscular junction development
negative regulation of sodium ion transport
protein ubiquitination
negative regulation of vascular endothelial growth factor receptor signaling pathway
T cell activation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
blood vessel morphogenesis
regulation of dendrite morphogenesis
regulation of synapse organization
protein K63-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
protein C-terminus binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
sodium channel inhibitor activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
phosphoserine binding
phosphothreonine binding
ubiquitin protein ligase activity
proline-rich region binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity