68515

• Gene Symbol: Pfn1
• Gene Name: profilin 1
• Gene Aliases: Pfn
• Chromosome Location: Chr.11: 70651847 - 70654650 on Build GRCm38
• UniGene ID: Mm.2647
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pfn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011072.4	NP_035202.1	3	530
GenBank mRNA	AK011066.1	-	3	515
	AK028117.1	-	3	481
	AK150780.1	-	3	487
	AK152491.1	-	3	516
	AK160191.1	-	3	516
	BC002080.1	-	3	503	3490976
	X14425.1	-	3	419

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005022, BT007001, J03191, BC002475, GU727630, and others.
This siRNA also targets the following transcripts in Rat: NM_022511, FQ232047, FQ227505, FQ232749, FQ228171, and others.

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, cytoskeletal protein, non-motor actin binding protein

Gene Ontology Categories:

Process(es)

neural tube closure
regulation of transcription from RNA polymerase II promoter
regulation of actin polymerization or depolymerization
positive regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
negative regulation of actin filament bundle assembly
positive regulation of ATPase activity
sequestering of actin monomers
positive regulation of transcription from RNA polymerase II promoter
positive regulation of viral transcription
protein stabilization
positive regulation of DNA metabolic process
positive regulation of stress fiber assembly
negative regulation of stress fiber assembly
positive regulation of ruffle assembly

Function(s)

adenyl-nucleotide exchange factor activity
actin binding
actin monomer binding
receptor binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Rho GTPase binding
poly(A) RNA binding
proline-rich region binding