68647

• Gene Symbol: Numb
• Gene Name: numb gene homolog (Drosophila)
• Gene Aliases: Nb
• Chromosome Location: Chr.12: 83794034 - 83921934 on Build GRCm38
• UniGene ID: Mm.4390
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Numb
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001136075.2	NP_001129547.1	6	600
	NM_001272055.1	NP_001258984.1	5	567
	NM_001272056.1	NP_001258985.1	7	797
	NM_010949.2	NP_035079.1	6	600
GenBank mRNA	AF169191.1	-	5	552
	AF169192.1	-	6	585
	AF170709.1	-	6	585
	AK004553.1	-	8	822
	BC033459.1	-	8	838	3991630
	BC050108.1	-	9	857
	U70674.1	-	7	718

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003744, NM_001005743, NM_001005745, NM_001005744, BX248781, and others.
This siRNA also targets the following transcripts in Rat: NM_133287, DQ336703, DQ336702, AB210108, BC166596, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

multicellular organism development
nervous system development
neuroblast proliferation
axonogenesis
lateral ventricle development
neuroblast division in subventricular zone
positive regulation of cell migration
positive regulation of polarized epithelial cell differentiation
forebrain development
adherens junction organization
regulation of neuron differentiation
negative regulation of Notch signaling pathway
positive regulation of neurogenesis
positive regulation of dendrite morphogenesis
lung epithelial cell differentiation
negative regulation of protein localization to plasma membrane

Function(s)

protein binding
beta-catenin binding
alpha-catenin binding
cadherin binding