68715

• Gene Symbol: Pitx2
• Gene Name: paired-like homeodomain transcription factor 2
• Gene Aliases: 9430085M16Rik, Brx1, Brx1b, Munc30, Otlx2, Ptx2, Rieg
• Chromosome Location: Chr.3: 129199878 - 129219594 on Build GRCm38
• UniGene ID: Mm.246804
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pitx2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042502.2	NP_001035967.1	2	879
	NM_001042504.2	NP_001035969.1	3	370
	NM_001286942.1	NP_001273871.1	4	469
	NM_001287048.1	NP_001273977.1	2	879
	NM_011098.4	NP_035228.2	4	508
GenBank mRNA	AB006320.1	-	2	432
	AB006321.1	-	4	468
	AF048723.1	-	3	307
	AF048724.1	-	2	840
	AF201091.1	-	2	206
	AK034846.1	-	1	1738
	AK035083.1	-	2	537
	AM940438.1	-	3	174
	AM940439.1	-	2	132
	BC075660.1	-	2	544	30606653
	U70132.1	-	1	29
	U80010.1	-	4	443
	U80011.1	-	3	323
	U80036.1	-	3	341

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
patterning of blood vessels
vasculogenesis
in utero embryonic development
neuron migration
extraocular skeletal muscle development
atrioventricular valve development
cardiac neural crest cell migration involved in outflow tract morphogenesis
pulmonary myocardium development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
determination of left/right symmetry
heart development
skeletal muscle tissue development
myoblast fusion
anatomical structure morphogenesis
organ morphogenesis
Wnt signaling pathway
subthalamic nucleus development
hypothalamus cell migration
pituitary gland development
lung development
regulation of cell migration
embryonic camera-type eye development
embryonic hindlimb morphogenesis
vascular smooth muscle cell differentiation
deltoid tuberosity development
regulation of cell proliferation
odontogenesis
camera-type eye development
positive regulation of DNA binding
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
spleen development
embryonic digestive tract morphogenesis
cardiac muscle tissue development
cardiac muscle cell differentiation
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle cell development
digestive system development
ventricular septum morphogenesis
left lung morphogenesis
pulmonary vein morphogenesis
superior vena cava morphogenesis
endodermal digestive tract morphogenesis
iris morphogenesis
cell proliferation involved in outflow tract morphogenesis
left/right axis specification
positive regulation of myoblast proliferation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
phosphoprotein binding