68845

• Gene Symbol: Ppara
• Gene Name: peroxisome proliferator activated receptor alpha
• Gene Aliases: 4933429D07Rik, AW742785, Nr1c1, PPAR-alpha, PPARalpha, Ppar
• Chromosome Location: Chr.15: 85728192 - 85806851 on Build GRCm38
• UniGene ID: Mm.212789
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ppara
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113418.1	NP_001106889.1	4, 5	584
	NM_011144.6	NP_035274.2	4, 5	822
GenBank mRNA	AK035676.1	-	4, 5	823
	AK081709.1	-	4, 5	585
	AK149460.1	-	4, 5	521
	BC016892.1	-	4, 5	815	4222384
	X57638.1	-	4, 5	543

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013196, XM_006242152, XM_006242151, XM_006242153, XM_006242154, and others.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
fatty acid metabolic process
epidermis development
regulation of gene expression
negative regulation of macrophage derived foam cell differentiation
negative regulation of receptor biosynthetic process
negative regulation of cholesterol storage
negative regulation of sequestering of triglyceride
regulation of fatty acid metabolic process
intracellular receptor signaling pathway
negative regulation of protein binding
negative regulation of appetite
response to insulin
circadian regulation of gene expression
behavioral response to nicotine
wound healing
lipoprotein metabolic process
regulation of circadian rhythm
steroid hormone mediated signaling pathway
positive regulation of gluconeogenesis
negative regulation of blood pressure
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fatty acid oxidation
rhythmic process
enamel mineralization
regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
negative regulation of neuron death
negative regulation of transcription regulatory region DNA binding

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
drug binding
zinc ion binding
lipid binding
phosphatase binding
protein domain specific binding
ubiquitin conjugating enzyme binding
protein complex binding
sequence-specific DNA binding
metal ion binding
protein heterodimerization activity
NFAT protein binding
MDM2/MDM4 family protein binding