68858

• Gene Symbol: Eif2ak2
• Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
• Gene Aliases: 2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik
• Chromosome Location: Chr.17: 78852550 - 78882572 on Build GRCm38
• UniGene ID: Mm.378990
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Eif2ak2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011163.4	NP_035293.1	3	363
GenBank mRNA	AK028602.1	-	3	363
	M93567.1	-	3	305

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019335, XM_008764426, XM_008764425, L29281.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
positive regulation of cytokine production
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
translation
protein phosphorylation
response to virus
response to toxic substance
phosphorylation
negative regulation of translation
endoplasmic reticulum unfolded protein response
response to lipopolysaccharide
positive regulation of chemokine production
positive regulation of stress-activated MAPK cascade
response to vitamin E
negative regulation of osteoblast proliferation
response to interferon-alpha
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of viral genome replication
innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
defense response to virus
regulation of NLRP3 inflammasome complex assembly
positive regulation of NIK/NF-kappaB signaling
regulation of hematopoietic progenitor cell differentiation
regulation of hematopoietic stem cell proliferation
regulation of hematopoietic stem cell differentiation

Function(s)

nucleotide binding
RNA binding
double-stranded RNA binding
protein kinase activity
protein serine/threonine kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
poly(A) RNA binding