69369

• Gene Symbol: Stat5a
• Gene Name: signal transducer and activator of transcription 5A
• Gene Aliases: AA959963, STAT5
• Chromosome Location: Chr.11: 100859180 - 100885169 on Build GRCm38
• UniGene ID: Mm.277403
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Stat5a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001164062.1	NP_001157534.1	11	1422
	NM_011488.3	NP_035618.1	12	1652
GenBank mRNA	AK090254.1	-	6	3659
	AK154070.1	-	11	1387
	AY299491.1	-	11	1400
	AY299492.1	-	11	1400
	BC008998.1	-	11	1359	3482404
	BC013274.1	-	12	1611	4036030
	EU249543.1	-	11	1391
	U21103.1	-	12	1500
	U36502.1	-	12	1490
	Z48538.1	-	11	1412

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003152, L41142, DQ471288, U43185, AK301457, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

allantoin metabolic process
luteinization
natural killer cell differentiation
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
signal transduction
JAK-STAT cascade
female pregnancy
lactation
positive regulation of cell proliferation
peptidyl-tyrosine phosphorylation
regulation of steroid metabolic process
cytokine-mediated signaling pathway
taurine metabolic process
lipid storage
regulation of cell adhesion
regulation of epithelial cell differentiation
mammary gland development
positive regulation of natural killer cell differentiation
negative regulation of mast cell apoptotic process
T cell differentiation in thymus
prolactin signaling pathway
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of activated T cell proliferation
T cell homeostasis
negative regulation of apoptotic process
response to peptide hormone
positive regulation of interleukin-2 biosynthetic process
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of lymphocyte differentiation
negative regulation of erythrocyte differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
positive regulation of natural killer cell mediated cytotoxicity
creatinine metabolic process
development of secondary female sexual characteristics
development of secondary male sexual characteristics
Peyer's patch development
positive regulation of inflammatory response
mammary gland involution
positive regulation of mast cell differentiation
JAK-STAT cascade involved in growth hormone signaling pathway
prostate gland epithelium morphogenesis
epithelial cell differentiation involved in prostate gland development
mammary gland epithelium development
positive regulation of mast cell proliferation
cellular response to granulocyte macrophage colony-stimulating factor stimulus

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
protein binding
protein phosphatase binding
sequence-specific DNA binding