69452

• Gene Symbol: Srebf1
• Gene Name: sterol regulatory element binding transcription factor 1
• Gene Aliases: ADD-1, ADD1, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, SREBP1, SREBP1c, bHLHd1
• Chromosome Location: Chr.11: 60199089 - 60222686 on Build GRCm38
• UniGene ID: Mm.278701
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Srebf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011480.3	NP_035610.1	7	1270
GenBank mRNA	AB017337.1	-	6	1086
	AF374266.1	-	6	1034
	AK052628.1	-	7	1271
	AK150052.1	-	7	1259
	AK154424.1	-	7	1238
	AK169607.1	-	7	1271
	BC006051.1	-	4	406
	BC056922.1	-	7	1252	6824948

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001276707, NM_001276708, XM_008767879, AF286469, AF286470.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of heart rate by chemical signal
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
insulin receptor signaling pathway
lipid biosynthetic process
cellular response to starvation
response to glucose
positive regulation of triglyceride biosynthetic process
regulation of fatty acid metabolic process
positive regulation of histone deacetylation
regulation of protein stability
positive regulation of cholesterol biosynthetic process
positive regulation of fatty acid biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
regulation of insulin secretion
regulation of mitophagy
regulation of protein targeting to mitochondrion

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
protein complex binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity