69714

• Gene Symbol: Timp2
• Gene Name: tissue inhibitor of metalloproteinase 2
• Gene Aliases: D11Bwg1104e, Timp-2
• Chromosome Location: Chr.11: 118301061 - 118355411 on Build GRCm38
• UniGene ID: Mm.206505
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Timp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011594.3	NP_035724.2	2	532
GenBank mRNA	AK032818.1	-	2	446
	AK081522.1	-	2	628
	AK144236.1	-	2	447
	AK194058.1	-	1	86
	AY622854.1	-	1	62
	BC049126.1	-	2	429	6821553
	M82858.1	-	2	427
	M93954.1	-	2	219
	X62622.1	-	2	437

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
response to hormone
negative regulation of peptidase activity
negative regulation of endopeptidase activity
regulation of cAMP metabolic process
regulation of Rap protein signal transduction
response to cytokine
positive regulation of catalytic activity
negative regulation of catalytic activity
regulation of MAPK cascade
positive regulation of MAPK cascade
regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of adenylate cyclase activity
negative regulation of proteolysis
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
negative regulation of membrane protein ectodomain proteolysis
cellular response to organic substance

Function(s)

protease binding
enzyme inhibitor activity
integrin binding
enzyme activator activity
metalloendopeptidase inhibitor activity
peptidase inhibitor activity
metal ion binding