69906

• Gene Symbol: Wrn
• Gene Name: Werner syndrome homolog (human)
• Gene Aliases: AI846146
• Chromosome Location: Chr.8: 33234372 - 33385545 on Build GRCm38
• UniGene ID: Mm.228805
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wrn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001122822.1	NP_001116294.1	2, 3	189
	NM_011721.4	NP_035851.3	2, 3	299
GenBank mRNA	AF091215.1	-	2, 3	253
	AF241636.1	-	2, 3	314
	AK143778.1	-	2, 3	277
	AK153824.1	-	3, 4	382
	AK158180.1	-	2, 3	160
	AK165679.1	-	2, 3	546
	AK171490.1	-	2, 3	300
	BC050921.1	-	2, 3	244	6408901
	BC060700.1	-	2, 3	244	6408901
	D86526.1	-	2, 3	269
	D86527.1	-	2, 3	269

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA synthesis involved in DNA repair
replicative cell aging
nucleobase-containing compound metabolic process
DNA metabolic process
DNA replication
DNA repair
base-excision repair
double-strand break repair
DNA recombination
cellular response to DNA damage stimulus
response to oxidative stress
cell aging
metabolic process
cellular response to starvation
response to UV-C
multicellular organism aging
replication fork processing
nucleolus to nucleoplasm transport
DNA duplex unwinding
regulation of growth rate
regulation of apoptotic process
cellular metabolic process
positive regulation of hydrolase activity
cellular response to gamma radiation
nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleotide binding
magnesium ion binding
Y-form DNA binding
bubble DNA binding
nucleic acid binding
DNA binding
DNA helicase activity
catalytic activity
ATP-dependent DNA helicase activity
helicase activity
nuclease activity
exonuclease activity
protein binding
ATP binding
ATP-dependent helicase activity
3'-5' exonuclease activity
four-way junction helicase activity
hydrolase activity
ATPase activity
manganese ion binding
protein complex binding
phosphoric ester hydrolase activity
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
metal ion binding
G-quadruplex DNA binding