70002

• Gene Symbol: Xdh
• Gene Name: xanthine dehydrogenase
• Gene Aliases: XO, Xor, Xox-1, Xox1
• Chromosome Location: Chr.17: 73883895 - 73950196 on Build GRCm38
• UniGene ID: Mm.11223
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Xdh
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011723.3	NP_035853.2	4, 5	388
GenBank mRNA	AK034256.1	-	4, 5	338
	AK143412.1	-	4, 5	337
	AK144700.1	-	4, 5	340
	AK161529.1	-	4, 5	339
	AK164764.1	-	4, 5	331
	BC141183.1	-	4, 5	363	9055795
	X62932.1	-	4, 5	322

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000379, U06117, D11456, U39487.

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
activation of cysteine-type endopeptidase activity involved in apoptotic process
lactation
xanthine catabolic process
response to aluminum ion
negative regulation of gene expression
regulation of epithelial cell differentiation
bone resorption
negative regulation of endothelial cell differentiation
negative regulation of protein kinase B signaling
oxidation-reduction process
positive regulation of p38MAPK cascade
negative regulation of vascular endothelial growth factor signaling pathway
positive regulation of reactive oxygen species metabolic process
negative regulation of vasculogenesis

Function(s)

catalytic activity
xanthine dehydrogenase activity
xanthine oxidase activity
iron ion binding
protein binding
UDP-N-acetylmuramate dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the aldehyde or oxo group of donors
molybdenum ion binding
protein homodimerization activity
molybdopterin cofactor binding
metal ion binding
flavin adenine dinucleotide binding
iron-sulfur cluster binding
2 iron, 2 sulfur cluster binding