701

• Gene Symbol: ITK
• Gene Name: IL2 inducible T-cell kinase
• Gene Aliases: EMT, LPFS1, LYK, PSCTK2
• Chromosome Location: Chr.5: 157180896 - 157255185 on Build GRCh38
• UniGene ID: Hs.558348
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005546.3	NP_005537.3	2, 3	333
GenBank mRNA	AB209622.1	-	2, 3	386
	AK303609.1	-	2, 3	299
	AK312846.1	-	2, 3	302
	BC109077.2	-	2, 3	324	40034274
	BC109078.1	-	2, 3	324	40034276
	D13720.1	-	2, 3	333

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

cytokine production
NK T cell differentiation
adaptive immune response
cellular defense response
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
activation of phospholipase C activity
interferon-gamma production
interleukin-4 production
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
T cell activation
regulation of cell proliferation
innate immune response
T cell receptor signaling pathway

Function(s)

non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
metal ion binding