7018

• Gene Symbol: GJA1
• Gene Name: gap junction protein alpha 1
• Gene Aliases: AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA
• Chromosome Location: Chr.6: 121435577 - 121449744 on Build GRCh38
• UniGene ID: Hs.700699
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GJA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000165.4	NP_000156.1	2	586
GenBank mRNA	AK223289.1	-	2	517
	AK295460.1	-	3	431
	AK297402.1	-	2	278
	AK297764.1	-	3	470
	AK312324.1	-	2	528
	BC026329.1	-	2	402	4794131
	CR541660.1	-	1	314
	M65188.1	-	2	479
	X52947.1	-	2	471

More Information

Panther Classification:

Molecular Function -

gap junction

Gene Ontology Categories:

Process(es)

osteoblast differentiation
in utero embryonic development
neuron migration
negative regulation of endothelial cell proliferation
heart looping
regulation of heart rate
epithelial cell maturation
lens development in camera-type eye
chronic inflammatory response
positive regulation of glomerular filtration
endothelium development
atrial ventricular junction remodeling
transport
apoptotic process
muscle contraction
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
heart development
adult heart development
response to pH
response to glucose
vascular transport
positive regulation of gene expression
negative regulation of gene expression
cell communication by chemical coupling
cell communication by electrical coupling
positive regulation of cell communication by chemical coupling
ATP transport
gap junction assembly
negative regulation of cell growth
regulation of bone mineralization
positive regulation of insulin secretion
ion transmembrane transport
response to fluid shear stress
embryonic digit morphogenesis
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
response to peptide hormone
positive regulation of osteoblast differentiation
positive regulation of protein catabolic process
positive regulation of striated muscle tissue development
positive regulation of vasoconstriction
positive regulation of vasodilation
regulation of bone remodeling
blood vessel morphogenesis
neuron projection morphogenesis
protein oligomerization
regulation of calcium ion transport
negative regulation of cardiac muscle cell proliferation
milk ejection
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
negative regulation of wound healing
cellular response to mechanical stimulus
atrial cardiac muscle cell action potential
cell communication by electrical coupling involved in cardiac conduction
negative regulation of DNA biosynthetic process
regulation of bicellular tight junction assembly
positive regulation of behavioral fear response

Function(s)

signal transducer activity
receptor binding
gap junction channel activity
protein binding
ion transmembrane transporter activity
SH3 domain binding
PDZ domain binding
beta-tubulin binding
connexin binding
gap junction channel activity involved in cardiac conduction electrical coupling
scaffold protein binding
gap junction channel activity involved in cell communication by electrical coupling